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Table 3 Most important associations between biochemical parameters, gut microbiota and BMI SDS represented by regression coefficient β (p value)

From: Differences in gut microbiota composition between obese and lean children: a cross-sectional study

 

Biochemical markers

 

Leukocytes

Glucose

Insulin

HDL-C

TG

TC

ALT

AST

hs-CRP

 

(%)

(mg/dl)

(μU/ml)

(mg/dl)

(mg/dl)

(mg/dl)

(U/l)

(U/l)

(mg/l)

Quantitative plating

         

Bacteroides fragilis group

 

−1.469

 

−1.677

 

−6.926

   
 

(0.237)

 

(0.099)

 

(0.497)

   

Bifidobacterium spp.

 

0.830

   

5.673

−1.619

−0.124

 
 

(0.631)

   

(0.719)

(0.753)

(0.969)

 

Clostridium spp.

−0.276

0.071

−3.725

 

2.322

22.353

 

−3.598

 

(0.562)

(0.967)

(0.343)

 

(0.932)

(0.181)

 

(0.245)

 

Staphylococcus spp.

   

1.718

−30.933

−32.137

   
   

(0.414)

(0.381)

(0.122)

   

Lactobacillus spp.

  

2.040

     

0.171

  

(0.497)

     

(0.007)*

qPCR

         

Bacteroides-Prevotella-Porphyromonas spp.

   

−0.668

     
   

(0.771)

     

Bifidobacterium spp.

         

Clostridium coccoides-Eubacterium rectale group

0.860

0.825

 

1.259

 

33.654

−3.686

−6.465

0.285

(0.107)

(0.810)

 

(0.688)

 

(0.234)

(0.518)

(0.189)

(0.292)

Clostridium leptum group

         

Staphylococcus spp.

    

11.856

    
    

(0.481)

    

Lactobacillus spp.

 

−1.307

1.342

 

17.604

−5.764

 

6.274

−0.004

 

(0.518)

(0.703)

 

(0.468)

(0.717)

 

(0.139)

(0.979)

BMI SDS

0.726

2.449

1.008

2.588

75.925

29.824

19.310

10.655

0.181

(0.469)

(0.392)

(0.900)

(0.406)

(0.086)

(0.207)

(0.072)

(0.117)

(0.390)

  1. Regression coefficient with 95% CI. *Significant association with p value < 0.05.