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Fig. 1 | Gut Pathogens

Fig. 1

From: miR-125a-5p regulates the sialyltransferase ST3GAL1 in murine model of human intestinal campylobacteriosis

Fig. 1

In silico predicted conserved murine and human targets of miR-125a-5p and miR-615-3p. A The Venn diagram presents interfaces of overlapping targets of miR-125a-5p and miR-615-3p within the mucin-type O-glycosylation pathway of which the glycosyltransferases St3gal1 and B4galt1 are conserved in human and mouse, respectively. B Excerpt of the KEGG signalling pathway enrichment analysis of mucin-type O-glycosylation in mouse and human [20]. Marked by the red asterisks are the specific steps in the glycosylation that might be modified by miR-125a-5p and miR-615-3p interaction. C Two binding sites of miR-125a-5p were identified in the 3’UTR of the murine St3gal1 using RNAhybrid [21]

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Gut Pathogens

ISSN: 1757-4749