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  2. The liver plays an important role in production and metabolism of homocysteine (Hcy), which has been reported to be involved in liver injury. In our previous work, we confirm that Hcy can induce liver injury b...

    Authors: Kun Xiao, Shengchao Ma, Long Xu, Ning Ding, Hui Zhang, Lin Xie, Lingbo Xu, Yun Jiao, Huiping Zhang and Yideng Jiang

    Citation: Gut Pathogens 2021 13:63

    Content type: Research

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  3. The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) has a tropism for the gastrointestinal tract and several studies have shown an alteration of the gut microbiota in hospitalized infected patient...

    Authors: Flavio De Maio, Gianluca Ianiro, Gaetano Coppola, Francesco Santopaolo, Valeria Abbate, Delia Mercedes Bianco, Fabio Del Zompo, Giuseppe De Matteis, Massimo Leo, Antonio Nesci, Alberto Nicoletti, Maurizio Pompili, Giovanni Cammarota, Brunella Posteraro, Maurizio Sanguinetti, Antonio Gasbarrini…

    Citation: Gut Pathogens 2021 13:62

    Content type: Letter to the Editor

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  4. Gas-producing perianal abscess raises the possibility of clostridial infection, with Clostridium perfringens being the most common causative agent, which is highly lethal if untreated timely. As the treatment of ...

    Authors: Yang Sun, Haotian Bai, Ji Qu, Jichao Liu, Jincheng Wang, Zhenwu Du and Linlin Feng

    Citation: Gut Pathogens 2021 13:61

    Content type: Case report

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  5. Helicobacter pylori (Hp) eradication has been used for many years. Yet, the impact of this eradication on the normal gastric microflora is not well understood. In this study, we explored the effect of eradication...

    Authors: Li-Qi Mao, Yan-Lin Zhou, Shuang-Shuang Wang, Lin Chen, Yue Hu, Lei-Min Yu, Jing-Ming Xu and Bin Lyu

    Citation: Gut Pathogens 2021 13:60

    Content type: Research

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  7. Through an arsenal of microbial enzymes, the gut microbiota considerably contributes to human metabolic processes, affecting nutrients, drugs, and environmental poisons. Azoreductases are a predominant group o...

    Authors: Sara A. Zahran, Marwa Ali-Tammam, Amal E. Ali and Ramy K. Aziz

    Citation: Gut Pathogens 2021 13:58

    Content type: Short report

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  8. The burden of Helicobacter pylori-induced gastric cancer varies based on predominant H. pylori population in various geographical regions. Vietnam is a high H. pylori burden country with the highest age-standardi...

    Authors: Trang Hoa Nguyen, Trang Thi My Ho, Thien-Phuc Nguyen-Hoang, Shamsul Qumar, Thuc Tran Dang Pham, Quy Nhuan Bui, Dieter Bulach, Thuy-Vy Nguyen and Motiur Rahman

    Citation: Gut Pathogens 2021 13:57

    Content type: Research

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  9. Recently, the role of endogenous microbiota and the genotype-microbiota correlation in inflammatory bowel disease (IBD) pathogenesis have been highlighted. However, fungi, as the second most prevalent resident...

    Authors: Niusha Sharifinejad, Seyed Hamidreza Mozhgani, Mahmood Bakhtiyari and Elaheh Mahmoudi

    Citation: Gut Pathogens 2021 13:56

    Content type: Research

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  10. Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens.

    Authors: Seung Woo Ahn, Se Hee Lee, Uh Jin Kim, Hee-Chang Jang, Hak-Jong Choi, Hyon E. Choy, Seung Ji Kang and Seong Woon Roh

    Citation: Gut Pathogens 2021 13:55

    Content type: Genome Report

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  11. Innovative research highlighted the probable connection between autism spectrum disorder (ASD) and gut microbiota as many autistic individuals have gastrointestinal problems as co-morbidities. This review emph...

    Authors: Laila Al-Ayadhi, Naima Zayed, Ramesa Shafi Bhat, Nadine M. S. Moubayed, May N. Al-Muammar and Afaf El-Ansary

    Citation: Gut Pathogens 2021 13:54

    Content type: Review

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  12. To comprehensively analyze the risk factors, clinical characteristics, outcomes, and prognostic factors of Cytomegalovirus (CMV) enteritis.

    Authors: Pai-Jui Yeh, Cheng-Tang Chiu, Ming-Wei Lai, Ren-Chin Wu, Chien-Ming Chen, Chia-Jung Kuo, Jun-Te Hsu, Ming-Yao Su, Wei-Pin Lin, Tsung-Hsing Chen and Puo-Hsien Le

    Citation: Gut Pathogens 2021 13:53

    Content type: Research

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  13. Dysregulated gut microbiota is one of major pathogenic factors in the development of colitis. Dock2 acts as a guanine nucleotide exchange factor (GEF) and activates small G protein RAC1. Our previous study sho...

    Authors: Yuan Xie, Jun Chen, Bing Wu, Tiansheng He, Lu Xie and Zhiping Liu

    Citation: Gut Pathogens 2021 13:52

    Content type: Research

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  14. Anastomotic failure causes morbidity and mortality even in technically correct anastomoses. Initial leaks must be prevented by mucosal reapproximation across the anastomosis. Healing is a concerted effort betw...

    Authors: Emilie E. Vomhof-DeKrey, Allie Stover and Marc D. Basson

    Citation: Gut Pathogens 2021 13:51

    Content type: Research

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  15. A strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the deve...

    Authors: A. L. Cunningham, J. W. Stephens and D. A. Harris

    Citation: Gut Pathogens 2021 13:50

    Content type: Review

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  17. Campylobacter jejuni (C. jejuni) is accountable for more than 400 million cases of gastroenteritis each year and is listed as a high-priority gut pathogen by the World Health Organization (WHO). Although the acut...

    Authors: Chandan Gorain, Afruja Khan, Ankita Singh, Samiran Mondal and Amirul Islam Mallick

    Citation: Gut Pathogens 2021 13:48

    Content type: Research

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  19. In the wake of emergence of antimicrobial resistance, bioactive phytochemical compounds are proving to be important therapeutic agents. The present study envisaged in silico molecular docking as well as in vit...

    Authors: Padikkamannil Abishad, Pollumahanti Niveditha, Varsha Unni, Jess Vergis, Nitin Vasantrao Kurkure, Sandeep Chaudhari, Deepak Bhiwa Rawool and Sukhadeo Baliram Barbuddhe

    Citation: Gut Pathogens 2021 13:46

    Content type: Research

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  20. The prevalence of antimicrobial resistance (AMR) among Gram-negative bacteria is alarmingly high. Reintroduction of colistin as last resort treatment in the infections caused by drug-resistant Gram-negative ba...

    Authors: Deepa Karki, Binod Dhungel, Srijana Bhandari, Anil Kunwar, Prabhu Raj Joshi, Basudha Shrestha, Komal Raj Rijal, Prakash Ghimire and Megha Raj Banjara

    Citation: Gut Pathogens 2021 13:45

    Content type: Research

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  21. Intestinal epithelial cells are challenged by mycotoxins and many bacterial pathogens. It was previously shown that the mycotoxin deoxynivalenol (DON) as well as Campylobacter (C.) jejuni have a negative impact o...

    Authors: Daniel Ruhnau, Claudia Hess, Barbara Doupovec, Bertrand Grenier, Dian Schatzmayr, Michael Hess and Wageha Awad

    Citation: Gut Pathogens 2021 13:44

    Content type: Research

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  22. Amoxicillin-resistant H. pylori strains are increasing worldwide. To explore the potential resistance mechanisms involved, the 3D structure modeling and access tunnel prediction for penicillin-binding proteins (P...

    Authors: Bahareh Attaran, Najmeh Salehi, Bahareh Ghadiri, Maryam Esmaeili, Shadi Kalateh, Mohammad Tashakoripour, Mahmoud Eshagh Hosseini and Marjan Mohammadi

    Citation: Gut Pathogens 2021 13:43

    Content type: Research

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  23. Campylobacter jejuni (C. jejuni) infections are of increasing importance worldwide. As a typical mucosal pathogen, the interaction of C. jejuni with mucins is a prominent step in the colonisation of mucosal surfa...

    Authors: De Xi, Lukas Hofmann, Thomas Alter, Ralf Einspanier, Stefan Bereswill, Markus M. Heimesaat, Greta Gölz and Soroush Sharbati

    Citation: Gut Pathogens 2021 13:42

    Content type: Research

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  24. Lentibacillus species are gram variable aerobic bacteria that live primarily in halophilic environments. Previous reports have shown that bacteria belonging to this species are primarily isolated from salty envir...

    Authors: Seung Woo Ahn, Se Hee Lee, Hong-Seok Son, Seong Woon Roh and Yoon-E Choi

    Citation: Gut Pathogens 2021 13:41

    Content type: Genome Report

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  25. Two different types of hypervirulent K. pneumoniae (HvKp), the MLST-11 and serotype K1/K2 strains, have been frequently described in recent studies. Although these two types of strains were described to be HvKp, ...

    Authors: Tsui-Chin Wang, Jung-Chung Lin, Jen-Chang Chang, Ya-Wen Hiaso, Ching-Hsun Wang, Sheng‑Kung Chiu, Chang-Phone Fung, Feng-Yee Chang and L. Kristopher Siu

    Citation: Gut Pathogens 2021 13:40

    Content type: Research

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  26. There are geographic variations in the genotypes of Helicobacter pylori (H. pylori) cagA, vacA, iceA, oipA and dupA. The aim of the study was to investigate the distribution of these genotypes among H. pylori str...

    Authors: Zhijing Xue, Hong Yang, Dongxing Su, Xiangfeng Song, Xin Deng, Changhong Yu, Chunhua Sun, Lihua He, Yuanhai You, Yanan Gong, Dongjie Fan, Lu Sun, Xiurui Han, Ruyue Fan, Maojun Zhang, Xiaomei Yan…

    Citation: Gut Pathogens 2021 13:39

    Content type: Research

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  27. The urea breath test (UBT) is widely used for diagnosing Helicobacter pylori infection. In the Shenzhen Kuichong People’s Hospital, some UBT findings were contradictory to the histology outcomes, therefore this s...

    Authors: Xiangyu Wang, Shuzhen Zhang, Eng Guan Chua, Yongsheng He, Xiaofeng Li, Aijun Liu, Haiting Chen, Michael J. Wise, Barry J. Marshall, Dayong Sun, Xuehong Li and Chin Yen Tay

    Citation: Gut Pathogens 2021 13:38

    Content type: Research

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  28. The classification of natural antimicrobials as potential antibiotic replacements is still hampered by the absence of clear biological mechanisms behind their mode of action. This study investigated the mechan...

    Authors: Igori Balta, Adela Marcu, Mark Linton, Carmel Kelly, Ozan Gundogdu, Lavinia Stef, Ioan Pet, Patrick Ward, Myriam Deshaies, Todd Callaway, Phittawat Sopharat, Gratiela Gradisteanu-Pircalabioru and Nicolae Corcionivoschi

    Citation: Gut Pathogens 2021 13:37

    Content type: Research

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  29. Even though the incidence of H. pylori infection among Malays in the Malay Peninsula is low, we observed a high H. pylori prevalence in Sumatra, which is the main residence of Indonesian Malays. H. pylori prevale...

    Authors: Ari Fahrial Syam, Langgeng Agung Waskito, Yudith Annisa Ayu Rezkitha, Rentha Monica Simamora, Fauzi Yusuf, Kanserina Esthera Danchi, Ahmad Fuad Bakry, Arnelis, Erwin Mulya, Gontar Alamsyah Siregar, Titong Sugihartono, Hasan Maulahela, Dalla Doohan, Muhammad Miftahussurur and Yoshio Yamaoka

    Citation: Gut Pathogens 2021 13:36

    Content type: Research

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  30. Non-typhoidal salmonellosis remains a pressing public health problem worldwide. Quinolones, particularly fluoroquinolones, are widely used to treat various infections, including non-typhoidal salmonellosis, wh...

    Authors: Sohyun Lee, Nanjoo Park, Sujung Yun, Eunseon Hur, Jiwon Song, Hanna Lee, Yongsug Kim and Sangryeol Ryu

    Citation: Gut Pathogens 2021 13:35

    Content type: Letter to the Editor

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  31. Norovirus genotype GII.3[P12] strains have been an important pathogen for sporadic gastroenteritis infection. In previous studies of GII.3[P12], the number of specimens and time span are relatively small, whic...

    Authors: Jianguang Fu, Jing Ai, Changjun Bao, Jun Zhang, Qingbin Wu, Liguo Zhu, Jianli Hu and Zheng Xing

    Citation: Gut Pathogens 2021 13:34

    Content type: Research

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  32. Diarrhea remains the leading cause of childhood illness in China. Better understanding of burden and etiology of diarrheal diseases is important for development of effective prevention measures.

    Authors: Hong-Lu Zhou, Theresa Bessey, Song-Mei Wang, Zhao-Jun Mo, Leslie Barclay, Jin-Xia Wang, Can-Jing Zhang, Jing-Chen Ma, Chao Qiu, Gan Zhao, Rong-Cheng Li, Yu-Liang Zhao, Baoming Jiang and Xuan-Yi Wang

    Citation: Gut Pathogens 2021 13:33

    Content type: Research

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  33. Although Escherichia coli is the most frequently isolated microorganism in acute biliary tract infections with bacteremia, data regarding its virulence are limited.

    Authors: Mahoko Ikeda, Tatsuya Kobayashi, Fumie Fujimoto, Yuta Okada, Yoshimi Higurashi, Keita Tatsuno, Shu Okugawa and Kyoji Moriya

    Citation: Gut Pathogens 2021 13:32

    Content type: Research

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  35. Mycobacterium avium subspecies paratuberculosis (MAP), the cause of Johne disease, is a slow growing mycobacterium. Viable MAP detection is difficult, inconstant and time-consuming. The purpose of this study was ...

    Authors: Robert J. Greenstein, Liya Su, Irene R. Grant, Antonio C. G. Foddai, Amy Turner, Jason S. Nagati, Sheldon T. Brown and Judith R. Stabel

    Citation: Gut Pathogens 2021 13:30

    Content type: Research

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  36. By 27 June 2020, almost half a million people had died due to COVID-19 infections. The susceptibility and severity of infection vary significantly across nations. The contribution of chronic viral and parasiti...

    Authors: Enas Fakhry Abdel-Hamed, Mohamed N. Ibrahim, Nahed E. Mostafa, Howayda S. F. Moawad, Nahla E. Elgammal, Ehab M. Darwiesh, Dina S. El-rafey, Nissreen E. ElBadawy, Emad Ali Al-Khoufi and Salwa I. Hindawi

    Citation: Gut Pathogens 2021 13:29

    Content type: Research

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  37. Poor self-care skills and personal hygiene resulted from limitations in learning and understanding, put intellectually disabled individuals at greater risk for intestinal parasitic infections (IPIs). Despite s...

    Authors: Mohammad Javad Abbaszadeh Afshar, Mehdi Mohebali, Sina Mohtasebi, Aref Teimouri, Bahareh Sedaghat and Reza Saberi

    Citation: Gut Pathogens 2021 13:28

    Content type: Review

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  38. Salmonella enterica subsp. enterica serovar Typhimurium (S. Typhimurium) is an important zoonotic agent worldwide. The aim of this work was to compare genetically 117 S. Typhimurium isolated from different source...

    Authors: Amanda Ap. Seribelli, Patrick da Silva, Marcelo Ferreira da Cruz, Fernanda de Almeida, Miliane R. Frazão, Marta I. C. Medeiros, Dália dos P. Rodrigues, Jalusa D. Kich, Leandro de Jesus Benevides, Siomar de C. Soares, Marc W. Allard and Juliana Pfrimer. Falcão

    Citation: Gut Pathogens 2021 13:27

    Content type: Research

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  39. Helicobacter cinaedi are motile, gram-negative spiral rods with a natural reservoir in the intestinal tract of hamsters and rhesus monkeys. In humans, H. cinaedi has been reported in different human infections li...

    Authors: Sofie Larsen Rasmussen, Iben Ørsted, Irene Harder Tarpgaard and Hans Linde Nielsen

    Citation: Gut Pathogens 2021 13:26

    Content type: Case report

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  40. Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer's disease (AD) worldwide. The prevalence of small intestinal bacterial overgrowth (SIBO) in PD patients is high. ...

    Authors: Xiaoqing Li, Xin Feng, Zhongxiang Jiang and Zheng Jiang

    Citation: Gut Pathogens 2021 13:25

    Content type: Review

    Published on:

  41. Cytomegalovirus (CMV)-associated gastrointestinal diseases usually occur in immunocompromised patients; however, few cases has also been described in healthy hosts despite still unclear pathological mechanisms...

    Authors: Daisuke Murakami, Hideaki Harada, Masayuki Yamato and Yuji Amano

    Citation: Gut Pathogens 2021 13:24

    Content type: Case report

    Published on:

  42. The cytotoxin-associated gene A (cagA) is one of the most important virulence factors of Helicobacter pylori (H. pylori). There is a highly polymorphic Glu-Pro-Ile-Tyr-Ala (EPIYA) repeat region in the C-terminal ...

    Authors: Zhijing Xue, Yuanhai You, Lihua He, Yanan Gong, Lu Sun, Xiurui Han, Ruyue Fan, Kangle Zhai, Yaming Yang, Maojun Zhang, Xiaomei Yan and Jianzhong Zhang

    Citation: Gut Pathogens 2021 13:23

    Content type: Research

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  43. Interferon-alpha (IFN-α) and nucleot(s)ide analogs (NAs) are first-line drugs for the treatment of chronic hepatitis B virus (HBV) infections. Generally, NAs target the reverse transcription of HBV pregenomic ...

    Authors: Gang Wang, Jun Guan, Nazif U. Khan, Guojun Li, Junwei Shao, Qihui Zhou, Lichen Xu, Chunhong Huang, Jingwen Deng, Haihong Zhu and Zhi Chen

    Citation: Gut Pathogens 2021 13:22

    Content type: Review

    Published on:

  44. Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial...

    Authors: Muhammad U. Sohail, Hebah A. Al Khatib, Asmaa A. Al Thani, Khalid Al Ansari, Hadi M. Yassine and Maha Al-Asmakh

    Citation: Gut Pathogens 2021 13:21

    Content type: Short Report

    Published on:

  45. One of the approaches to cure human immunodeficiency virus (HIV) is the use of therapeutic vaccination. We have launched the Provir/Latitude 45 study to identify conserved CTL epitopes in archived HIV-1 DNA ac...

    Authors: Patricia Recordon-Pinson, Annie Gosselin, Petronela Ancuta, Jean-Pierre Routy and Hervé Fleury

    Citation: Gut Pathogens 2021 13:20

    Content type: Short report

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  46. Colorectal cancer (CRC) is one of the top ten causes of cancer deaths in the world. Despite an increased prevalence of colorectal cancer has been documented from developing countries, there is no any report re...

    Authors: Yesuf Adem Siraj, Melesse Gebeyehu Biadgelign, Mensur Osman Yassin and Yohannes Zenebe Chekol

    Citation: Gut Pathogens 2021 13:19

    Content type: Research

    Published on:

  47. Infections caused by multidrug-resistant shigellae resistant to broad-spectrum cephalosporins are becoming more prevalent in the Middle East. We report a case of severe diarrhea due to a multiresistant Shigella f...

    Authors: M. John Albert, Prashant Purohit, Laurent Poirel, Glen Carter and Dieter Bulach

    Citation: Gut Pathogens 2021 13:18

    Content type: Case report

    Published on:

  48. Spontaneous bacterial peritonitis (SBP) is one of the most common infectious diseases in patients with cirrhosis and is associated with serious prognosis. A prevailing dogma posits that SBP is exacerbated by t...

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Abdul Rehman Zia Zaidi, Ali A. Rabaan, Alyaa Elhazmi and Awad Al-Omari

    Citation: Gut Pathogens 2021 13:17

    Content type: Research

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  49. Alteration in the gut microbiota has been proposed in irritable bowel syndrome (IBS) pathogenesis, especially in the diarrheal type (IBS-D). We conducted this study to evaluate the fecal microbiota in Thai IBS...

    Authors: Sawangpong Jandee, Suppana Chuensakul and Suppasil Maneerat

    Citation: Gut Pathogens 2021 13:16

    Content type: Research

    Published on:

  50. The membrane fusion protein (mfp) gene locus of Vibrio parahaemolyticus consists of two operons, cpsQ-mfpABC and mfpABC, which are both required for biofilm formation. ToxR and CalR are required for the full viru...

    Authors: Yiquan Zhang, Yue Qiu, Xingfan Xue, Miaomiao Zhang, Junfang Sun, Xue Li, Lingfei Hu, Zhe Yin, Wenhui Yang, Renfei Lu and Dongsheng Zhou

    Citation: Gut Pathogens 2021 13:15

    Content type: Research

    Published on:

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  • ISSN: 1757-4749 (electronic)

Gut Pathogens

ISSN: 1757-4749