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  1. Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer's disease (AD) worldwide. The prevalence of small intestinal bacterial overgrowth (SIBO) in PD patients is high. ...

    Authors: Xiaoqing Li, Xin Feng, Zhongxiang Jiang and Zheng Jiang

    Citation: Gut Pathogens 2021 13:25

    Content type: Review

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  2. Cytomegalovirus (CMV)-associated gastrointestinal diseases usually occur in immunocompromised patients; however, few cases has also been described in healthy hosts despite still unclear pathological mechanisms...

    Authors: Daisuke Murakami, Hideaki Harada, Masayuki Yamato and Yuji Amano

    Citation: Gut Pathogens 2021 13:24

    Content type: Case report

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  3. The cytotoxin-associated gene A (cagA) is one of the most important virulence factors of Helicobacter pylori (H. pylori). There is a highly polymorphic Glu-Pro-Ile-Tyr-Ala (EPIYA) repeat region in the C-terminal ...

    Authors: Zhijing Xue, Yuanhai You, Lihua He, Yanan Gong, Lu Sun, Xiurui Han, Ruyue Fan, Kangle Zhai, Yaming Yang, Maojun Zhang, Xiaomei Yan and Jianzhong Zhang

    Citation: Gut Pathogens 2021 13:23

    Content type: Research

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  4. Interferon-alpha (IFN-α) and nucleot(s)ide analogs (NAs) are first-line drugs for the treatment of chronic hepatitis B virus (HBV) infections. Generally, NAs target the reverse transcription of HBV pregenomic ...

    Authors: Gang Wang, Jun Guan, Nazif U. Khan, Guojun Li, Junwei Shao, Qihui Zhou, Lichen Xu, Chunhong Huang, Jingwen Deng, Haihong Zhu and Zhi Chen

    Citation: Gut Pathogens 2021 13:22

    Content type: Review

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  5. Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial...

    Authors: Muhammad U. Sohail, Hebah A. Al Khatib, Asmaa A. Al Thani, Khalid Al Ansari, Hadi M. Yassine and Maha Al-Asmakh

    Citation: Gut Pathogens 2021 13:21

    Content type: Short Report

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  6. One of the approaches to cure human immunodeficiency virus (HIV) is the use of therapeutic vaccination. We have launched the Provir/Latitude 45 study to identify conserved CTL epitopes in archived HIV-1 DNA ac...

    Authors: Patricia Recordon-Pinson, Annie Gosselin, Petronela Ancuta, Jean-Pierre Routy and Hervé Fleury

    Citation: Gut Pathogens 2021 13:20

    Content type: Short report

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  7. Colorectal cancer (CRC) is one of the top ten causes of cancer deaths in the world. Despite an increased prevalence of colorectal cancer has been documented from developing countries, there is no any report re...

    Authors: Yesuf Adem Siraj, Melesse Gebeyehu Biadgelign, Mensur Osman Yassin and Yohannes Zenebe Chekol

    Citation: Gut Pathogens 2021 13:19

    Content type: Research

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  8. Infections caused by multidrug-resistant shigellae resistant to broad-spectrum cephalosporins are becoming more prevalent in the Middle East. We report a case of severe diarrhea due to a multiresistant Shigella f...

    Authors: M. John Albert, Prashant Purohit, Laurent Poirel, Glen Carter and Dieter Bulach

    Citation: Gut Pathogens 2021 13:18

    Content type: Case report

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  9. Spontaneous bacterial peritonitis (SBP) is one of the most common infectious diseases in patients with cirrhosis and is associated with serious prognosis. A prevailing dogma posits that SBP is exacerbated by t...

    Authors: Saad Alhumaid, Abbas Al Mutair, Zainab Al Alawi, Abdul Rehman Zia Zaidi, Ali A. Rabaan, Alyaa Elhazmi and Awad Al-Omari

    Citation: Gut Pathogens 2021 13:17

    Content type: Research

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  10. Alteration in the gut microbiota has been proposed in irritable bowel syndrome (IBS) pathogenesis, especially in the diarrheal type (IBS-D). We conducted this study to evaluate the fecal microbiota in Thai IBS...

    Authors: Sawangpong Jandee, Suppana Chuensakul and Suppasil Maneerat

    Citation: Gut Pathogens 2021 13:16

    Content type: Research

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  11. The membrane fusion protein (mfp) gene locus of Vibrio parahaemolyticus consists of two operons, cpsQ-mfpABC and mfpABC, which are both required for biofilm formation. ToxR and CalR are required for the full viru...

    Authors: Yiquan Zhang, Yue Qiu, Xingfan Xue, Miaomiao Zhang, Junfang Sun, Xue Li, Lingfei Hu, Zhe Yin, Wenhui Yang, Renfei Lu and Dongsheng Zhou

    Citation: Gut Pathogens 2021 13:15

    Content type: Research

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  12. COVID-19 is an acute respiratory distress syndrome and is often accompanied by gastrointestinal symptoms. The SARS-CoV-2 has been traced not only in nasopharyngeal and mid-nasal swabs but also in stool and rec...

    Authors: Jyoti Chhibber-Goel, Sreehari Gopinathan and Amit Sharma

    Citation: Gut Pathogens 2021 13:14

    Content type: Commentary

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  13. This study aims to characterize, the gut and oral microbiome in Asian subjects with Crohn’s disease (CD) using whole genome shotgun sequencing, thereby allowing for strain-level comparison.

    Authors: Shijia Hu, Eileen Png, Michelle Gowans, David E. H. Ong, Paola Florez de Sessions, Jie Song and Niranjan Nagarajan

    Citation: Gut Pathogens 2021 13:13

    Content type: Research

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  14. The aim of this study was to determine the dominant species of bacteria found in blood cultures collected from patients under treatment in the tertiary inflammatory bowel disease (IBD) center in Poland. The do...

    Authors: Jolanta Gruszecka and Rafał Filip

    Citation: Gut Pathogens 2021 13:12

    Content type: Letter to the Editor

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  15. Gastric adenocarcinoma is associated with H. pylori infection and inflammation that can result in the dysbiosis of gastric microbiota. The association of intestinal microbiota with gastric adenocarcinoma subtypes...

    Authors: Virinder Sarhadi, Binu Mathew, Arto Kokkola, Tiina Karla, Milja Tikkanen, Hilpi Rautelin, Leo Lahti, Pauli Puolakkainen and Sakari Knuutila

    Citation: Gut Pathogens 2021 13:11

    Content type: Research

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  16. Clostridioides difficile infection (CDI) is a common hospital-associated diarrhea. Several antibiotics commonly associate with CDI; however, limited data are available on the duration of exposure prior to CDI. Mo...

    Authors: Khadijah M. Alammari and Abrar K. Thabit

    Citation: Gut Pathogens 2021 13:10

    Content type: Research

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  17. Shewanella xiamenensis has been reported in water environment and in patients and can act as the originator of oxacillinase in gram-negative bacteria. In order to assess genome plasticity and its functional prope...

    Authors: Thongpan Leangapichart, Linda Hadjadj, Philippe Gautret and Jean-Marc Rolain

    Citation: Gut Pathogens 2021 13:9

    Content type: Genome Report

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  18. Shiga toxin-producing Escherichia coli (STEC) is a pathotype of E. coli that causes enteric and systemic diseases ranging from diarrhoea to severe hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The...

    Authors: Walid Elmonir, Samar Shalaan, Amin Tahoun, Samy F. Mahmoud, Etab M. Abo Remela, Radwa Eissa, Hanem El-Sharkawy, Mustafa Shukry and Rasha N. Zahran

    Citation: Gut Pathogens 2021 13:8

    Content type: Research

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  19. SARS-CoV-2 has been detected not only in respiratory secretions, but also in stool collections. Here were sought to identify SARS-CoV-2 by enrichment next-generation sequencing (NGS) from fecal samples, and to...

    Authors: Andreas Papoutsis, Thomas Borody, Siba Dolai, Jordan Daniels, Skylar Steinberg, Brad Barrows and Sabine Hazan

    Citation: Gut Pathogens 2021 13:7

    Content type: Research

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  20. Bacillus cereus is ubiquitous in nature, found in environments such as soil, plants, air, and part of the insect and human gut microbiome. The ability to produce endospores and biofilms contribute to their pathog...

    Authors: Balakrishnan N. V. Premkrishnan, Cassie E. Heinle, Akira Uchida, Rikky W. Purbojati, Kavita K. Kushwaha, Alexander Putra, Puramadathil Sasi Santhi, Benjamin W. Y. Khoo, Anthony Wong, Vineeth Kodengil Vettath, Daniela I. Drautz-Moses, Ana Carolina M. Junqueira and Stephan C. Schuster

    Citation: Gut Pathogens 2021 13:6

    Content type: Genome Report

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  21. Intestinal fibrosis is a frequent complication of Crohn’s disease. However, the factors that cause chronicity and promote fibrogenesis are not yet understood.

    Authors: Dina Chokr, Marjorie Cornu, Christel Neut, Clovis Bortolus, Rogatien Charlet, Pierre Desreumaux, Silvia Speca and Boualem Sendid

    Citation: Gut Pathogens 2021 13:5

    Content type: Research

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  22. Campylobacter spp. enteritis is the most frequent bacterial enteritis in both adults and children and is sometimes a source of severe complications. Its diagnosis by culture suffers from a lack of sensitivity and...

    Authors: Justine Franco, Lucie Bénejat, Astrid Ducournau, Francis Mégraud, Philippe Lehours and Emilie Bessède

    Citation: Gut Pathogens 2021 13:4

    Content type: Research

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  23. The emerging intestinal pathogen Campylobacter concisus has been associated with prolonged diarrhoea and classic inflammatory bowel diseases (IBD) and was recently also linked with microscopic colitis (MC). Previ...

    Authors: Marta Emilie Yde Aagaard, Karina Frahm Kirk, Henrik Nielsen and Hans Linde Nielsen

    Citation: Gut Pathogens 2021 13:3

    Content type: Short report

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  24. Inflammatory bowel disease caused by microbial dysbiosis is an important factor contributing to colorectal cancer (CRC) initiation. The ‘driver-passenger’ model in human gut microbial dysbiosis suggests that ‘...

    Authors: Yijia Wang, Xuehua Wan, Xiaojing Wu, Chunze Zhang, Jun Liu and Shaobin Hou

    Citation: Gut Pathogens 2021 13:2

    Content type: Research

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  25. Colorectal adenomatous polyps (CAPs) are considered precancerous lesions of colorectal cancer (CRC). The gut microbiota participates in the process of digestion and, in the process, produces metabolites, mainl...

    Authors: Ciyan Chen, Min Niu, Junxi Pan, Na Du, Shumin Liu, Huanqin Li, Qiuyue He, Jian Mao, Yong Duan and Yan Du

    Citation: Gut Pathogens 2021 13:1

    Content type: Research

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  26. Helicobacter pullorum commonly colonized in the gastrointestinal tract of poultry and caused gastroenteritis. This bacterium could be transmitted to humans through contaminated food and caused colitis and hepatit...

    Authors: Guilan Zhou, Hao Liang, Yixin Gu, Changyan Ju, Lihua He, Pengbo Guo, Zhujun Shao, Jianzhong Zhang and Maojun Zhang

    Citation: Gut Pathogens 2020 12:56

    Content type: Research

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  27. The emergence and transmission of the mobile colistin resistance gene (mcr-1) threatened the extensive use of polymyxin antimicrobials. Accumulated evidence showed that the banning of colistin additive in livesto...

    Authors: Cong Shen, Lan-Lan Zhong, Furong Ma, Mohamed Abd El-Gawad El-Sayed Ahmed, Yohei Doi, Guili Zhang, Yang Liu, Songyin Huang, Hong-Yu Li, Liyan Zhang, Kang Liao, Yong Xia, Min Dai, Bin Yan and Guo-Bao Tian

    Citation: Gut Pathogens 2020 12:55

    Content type: Short report

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  28. The global emergence of plasmid-mediated colistin resistance (Col-R) conferred by mcr genes in gram-negative rods (GNRs) has jeopardized the last treatment option for multidrug-resistant bacterial infections in h...

    Authors: Humera Javed, Sidrah Saleem, Aizza Zafar, Aamir Ghafoor, Ahmad Bin Shahzad, Hasan Ejaz, Kashaf Junaid and Shah Jahan

    Citation: Gut Pathogens 2020 12:54

    Content type: Research

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  29. Cathelicidins are a class of antimicrobial peptide, and the murine cathelicidin-related antimicrobial peptide (mCRAMP) has been demonstrated in vitro to impair Salmonella enterica serovar Typhimurium proliferatio...

    Authors: Danisa M. Bescucci, Sandra T. Clarke, Catherine L. J. Brown, Valerie F. Boras, Tony Montina, Richard R. E. Uwiera and G. Douglas Inglis

    Citation: Gut Pathogens 2020 12:53

    Content type: Research

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  30. Quinolone prophylaxis is recommended for patients with advanced cirrhosis at high risk of spontaneous bacterial peritonitis (SBP) or with prior SBP. Yet, the impact of long-term antibiotic prophylaxis on the m...

    Authors: Marcus M. Mücke, Sabrina Rüschenbaum, Amelie Mayer, Victoria T. Mücke, Katharina M. Schwarzkopf, Stefan Zeuzem, Jan Kehrmann, René Scholtysik and Christian M. Lange

    Citation: Gut Pathogens 2020 12:51

    Content type: Research

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  31. Increasing evidence demonstrate that the gut microbiota is involved in the pathogenesis of liver diseases, and faecal microbiota transplantation is considered to be a promising new treatment option. However, t...

    Authors: Xiu-An Yang, Fengchun Lv, Ran Wang, Yange Chang, Yiming Zhao, Xinyu Cui, Haochen Li, Sixi Yang, Suting Li, Xuemin Zhao, Zhishuo Mo and Fang Yang

    Citation: Gut Pathogens 2020 12:50

    Content type: Research

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  32. The steady increase in the proportion of Non-typhoidal Salmonella (NTS) infections in humans represents a major health problem worldwide. The current study investigated the serovar distribution and antimicrobial ...

    Authors: Jobin John Jacob, Dhanalakshmi Solaimalai, Dhiviya Prabaa Muthuirulandi Sethuvel, Tanya Rachel, Praveena Jeslin, Shalini Anandan and Balaji Veeraraghavan

    Citation: Gut Pathogens 2020 12:49

    Content type: Research

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  33. MiR-146a, an effector mediator, targets Notch-1 and regulates the innate and adaptive immune systems response. Recently, we reported that Notch-1 signaling plays a key role in macrophage polarization and respo...

    Authors: Esra’a Keewan and Saleh A. Naser

    Citation: Gut Pathogens 2020 12:48

    Content type: Research

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  34. Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylatio...

    Authors: Yoshiki Okita, Minoru Koi, Koki Takeda, Ryan Ross, Bhramar Mukherjee, Erika Koeppe, Elena M. Stoffel, Joseph A. Galanko, Amber N. McCoy, Temitope O. Keku, Yoshinaga Okugawa, Takahito Kitajima, Yuji Toiyama, Eric Martens and John M. Carethers

    Citation: Gut Pathogens 2020 12:46

    Content type: Letter to the Editor

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  35. Based on MLST analyses the global population of C. difficile is distributed in eight clades, of which Clade 2 includes the “hypervirulent” NAP1/RT027/ST01 strain along with various unexplored sequence types (STs)...

    Authors: Josué Orozco-Aguilar, Alejandro Alfaro-Alarcón, Luis Acuña-Amador, Esteban Chaves-Olarte, César Rodríguez and Carlos Quesada-Gómez

    Citation: Gut Pathogens 2020 12:45

    Content type: Research

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  36. Plasmid-mediated resistance to the last-resort drugs: carbapenems and colistin is an emerging public health threat. The studies on the prevalence and co-expression of resistant genes among livestock and human ...

    Authors: Bijaya Muktan, Upendra Thapa Shrestha, Binod Dhungel, Bagish Chandra Mishra, Nabaraj Shrestha, Nabaraj Adhikari, Megha Raj Banjara, Bipin Adhikari, Komal Raj Rijal and Prakash Ghimire

    Citation: Gut Pathogens 2020 12:44

    Content type: Research

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  37. Community-acquired urinary tract infection (CA-UTI) could be caused by endogenous or exogenous routes. To show this relationship, we investigated molecular fingerprints and genotypes of paired Enterococcus faecal...

    Authors: Zohreh Ghalavand, Masoud Alebouyeh, Kiandokht Ghanati, Leila Azimi and Marjan Rashidan

    Citation: Gut Pathogens 2020 12:42

    Content type: Research

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  38. Colistin is still a widely used antibiotic in veterinary medicine although it is a last-line treatment option for hospitalized patients with infections caused by multidrug-resistant Gram-negative bacteria. Col...

    Authors: Bernd Neumann, Wiebke Rackwitz, Klaus-Peter Hunfeld, Stephan Fuchs, Guido Werner and Yvonne Pfeifer

    Citation: Gut Pathogens 2020 12:40

    Content type: Genome Report

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  39. After the failure of clarithromycin- and bismuth-based quadruple therapy (CBQT), levofloxacin- and bismuth-based quadruple therapy (LBQT) is recommended for Helicobacter pylori eradication. We compared the effica...

    Authors: Siya Kong, Keting Huang, Jun Wang, Xiaoyong Wang, Ningmin Yang, Yu Dong, Ya Zhuang, Yini Dang, Guoxin Zhang and Feng Ye

    Citation: Gut Pathogens 2020 12:39

    Content type: Research

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  40. Intestinal bacterial dysbiosis and increased gut permeability are associated with higher risk of developing type 1 diabetes (T1D) or celiac disease (CD). There is a lack of information on parasitism involved i...

    Authors: Ana M. Calderón de la Barca, Reyna S. Castillo-Fimbres, María Esther Mejía-León, Luis Quihui-Cota, Adrián Ochoa-Leyva and Sandra V. Aguayo-Patrón

    Citation: Gut Pathogens 2020 12:37

    Content type: Research

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  41. Helicobacter pylori bacterium is a major cause of gastritis. With increasing use of antibiotics to treat infections, mutation resistant strains have emerged in most human populations. To effectively treat patient...

    Authors: Yangxia Li, Tangshan Lv, Chaochao He, Hongyan Wang, David S. Cram, Linfu Zhou, Jun Zhang and Weiqin Jiang

    Citation: Gut Pathogens 2020 12:35

    Content type: Research

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  42. Hypervirulent Klebsiella pneumoniae (HVKp) infections have distinct clinical manifestations from classical K. pneumoniae infections. The hallmark of HVKp infections are liver abscess formation and metastatic infe...

    Authors: Atsushi Togawa, Michinobu Yoshimura, Chiemi Tokushige, Akira Matsunaga, Tohru Takata and Yasushi Takamatsu

    Citation: Gut Pathogens 2020 12:34

    Content type: Research

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  43. Metagenomic analysis of the gut microbiome and resistome is instrumental for understanding the dynamics of diarrheal pathogenesis and antimicrobial resistance transmission (AMR). Metagenomic sequencing of 20 d...

    Authors: Rituparna De, Asish Kumar Mukhopadhyay and Shanta Dutta

    Citation: Gut Pathogens 2020 12:32

    Content type: Research

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