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Table 2 Clinical and laboratory profile of all subjects

From: Elevated plasma and bile levels of corisin, a microbiota-derived proapoptotic peptide, in patients with severe acute cholangitis

 

Normal values

Non-AC group

AC group

P values

No of subjects

 

9

40

 

Systolic pressure

 < 120 mmHg

126.89 ± 8.7

128.60 ± 3.49

0.36

Diastolic pressure

 < 80 mmHg

76.73 ± 3.43

69.28 ± 1.94

0.04

Body temperature

36.1–37.2 °C

36.97 ± 0.20

36.87 ± 0.11

0.34

White blood cells

3,300–8,600/µL

8.05 ± 1.53

10.25 ± 0.80

0.08

Blood platelets

13.8–30.9 × 104 (µL)

230.80 ± 31.88

178.60 ± 12.74

0.07

Blood hemoglobin

11.6–16.5 g/dL

12.43 ± 0.61

11.68 ± 0.34

0.22

Blood total protein

6.5–8.0 g/dL

6.45 ± 0.29

6.45 ± 0.11

0.45

Blood albumin

4.0–5.2 g/dL

3.37 ± 0.23

3.09 ± 0.11

0.07

Blood total bilirubin

0.2–1.2 mg/dL

3.17 ± 0.88

3.40 ± 0.40

0.33

Blood direct bilirubin

0–0.3 mg/dL

2.12 ± 0.74

2.15 ± 0.42

0.49

Serum aspartate aminotransferase

 ≤ 30 U/L

176.20 ± 55.71

204.30 ± 36.52

0.46

Serum alanine transaminase

 ≤ 30 U/L

191.1 ± 53.2

155.20 ± 22.30

0.28

Serum γ-glutamyl transpeptidase

 ≤ 50 U/L

391.0 ± 138.2

382.8 ± 51.02

0.40

Serum alkaline phosphatase

38–113 U/L

272.70 ± 39.60

353.7 ± 46.57

0.44

Serum amylase

43–116 U/L

97.63 ± 29.56

82.75 ± 11.69

0.45

Serum Na

135–147 mmol/L

138.20 ± 1.61

137.5 ± 0.66

0.28

Serum K

3.3–4.8 mmol/L

4.04 ± 0.22

4.02 ± 0.09

0.31

Serum Cl

98–108 mmol/L

100.7 ± 2.42

100.1 ± 2.42

0.31

Serum procalcitonin

 < 0.05 ng/mL

1.56 ± 1.20

5.66 ± 2.03

0.07

Serum C-reactive protein

 ≤ 0.3 mg/dL

4.01 ± 1.77

9.97 ± 1.67

0.02

Blood urea nitrogen

7–24 mg/dL

18.10 ± 2.81

26.12 ± 3.56

0.37

Serum creatinine

 ≤ 0.70 mg/dL

1.40 ± 0.69

1.49 ± 0.25

0.04

Activated partial thromboplastin time

24–39 s

34.84 ± 4.43

35.82 ± 1.43

0.16

Prothrombin time (sec)

9–13 s

100.4 ± 11.81

80.92 ± 4.32

0.03

Plasma fibrin-degradation products

 < 5 µg/mL

5.35 ± 1.24

15.77 ± 3.09

0.04

Peripheral oxygen saturation

95–100%

97.44 ± 0.37

96.73 ± 0.40

0.15

Plasma IL-6

 < 17.4 pg/mL

178.20 ± 21.30

3088.0 ± 1294

0.02

Plasma TNFα

0–2.2 pg/mL

288.1 ± 12.9

551.4 ± 109.6

0.48

Plasma FasL

0.2–1.5 pg/mL

62.13 ± 6.36

70.16 ± 5.94

0.20

Bile IL-6

 < 10 pg/mL

259.70 ± 95.02

819.90 ± 299.60

0.05

Bile TNFα (pg/mL)

 < 5 pg/mL

374.70 ± 72.79

671.60 ± 122.80

0.13

Bile FasL (pg/mL)

0.5–2.5 pg/mL

115.50 ± 9.99

132.40 ± 18.25

0.17

  1. Data are expressed as the mean ± standard error of the mean
  2. TNF-α, tumor necrosis factor-α; IL-6, interleukin-6; AC, acute cholangitis
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Gut Pathogens

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