Table 2 Median (first quartile, third quartile) and a p-value of each individual candidate bacteria based on abundancy
Type | CRC positives | CRC negatives | p-value | |
|---|---|---|---|---|
Stool | ||||
Top family | Bacteroidaceae | 35,138 (20,473, 57,097) | 26,441 (19,861.25, 51,036.5) | 0.975 |
Coprobacillaceae | 22,037 (22,037, 22,037) | NA | ||
Enterobacteriaceae | 32,034 (11,517.5, 45,663) | 26,693 (12,241, 67,296) | 0.961 | |
Enterococcaceae | 21,837 (21,837, 21,837) | NA | ||
Lachnospiraceae | 20,466.5 (15,082.75, 26,686.25) | 9915 (8118.5, 18,518) | 0.006 | |
Neisseriaceae | 21,907 (21,907, 21,907) | NA | ||
Pasteurellaceae | 19,133.5 (11,658, 26,609) | 3078 (3078, 3078) | 0.221 | |
Prevotellaceae | 18,563 (13,833, 42,279) | 71,417 (29,676.5, 106,358) | 0.021 | |
Ruminococcaceae | 20,242 (13,254.25, 23,827) | 22,173 (9717.5, 26,917.5) | 0.946 | |
Streptococcaceae | 20,557 (245, 29,531) | NA | ||
Top species | Bacteroides cellulosilyticus | 16,964 (16,964, 16,964) | NA | |
Bacteroides vulgatus | 13,640 (6536, 26,760.5) | 6081 (3432.75, 12,740.5) | 0.090 | |
Coprobacillus cateniformis | 22,036 (22,036, 22,036) | NA | ||
Escherichia albertii | 14,601 (5602.75, 24,528.5) | 12,575 (4297.5, 33,527) | 0.752 | |
Haemophilus parainfluenzae | 12,201.5 (6813, 17,590) | NA | ||
Porphyromonas asaccharolytica | 20,356 (20,356, 20,356) | NA | ||
Prevotella copri | 16,278 (3795, 24,755) | 21,376 (3760, 57,922) | 0.441 | |
Sphingobacterium bambusae | 14,383 (14,383, 14,383) | NA | ||
Streptococcus vestibularis | 12,767 (12,767, 12,767) | NA | ||
Unclassified at Species level | 70,268 (58,857.5, 79,222) | 65,762 (57,502.75, 87,313.5) | 0.639 | |
Top phylum | Actinobacteria | 900 (396, 2108.5) | 1271.5 (415.75, 2160.75) | 0.770 |
Bacteroidetes | 82,999 (32,927, 102,132.5) | 89,034 (56,220.75, 104,966.25) | 0.429 | |
Firmicutes | 58,043 (47,733, 72,777.5) | 56,212 (38,746, 74,629.75) | 0.725 | |
Fusobacteria | 788.5 (271.5, 2717.75) | 13 (13, 13) | 0.114 | |
Nitrospirae | 325.5 (142, 1003.25) | 133 (63, 616.5) | 0.124 | |
Proteobacteria | 16,907 (11,310.5, 44,244.5) | 9314 (7409.25, 26,199.5) | 0.053 | |
Spirochaetes | 307.5 (118, 497) | NA | ||
Tenericutes | 226 (41, 1221.5) | 1262 (22, 2502) | 1.000 | |
Unclassified at Phylum level | 1884 (1154.5, 2477.5) | 1767.5 (1278.5, 2876.75) | 0.930 | |
Verrucomicrobia | 958.5 (271.25, 2273) | 210 (82.75, 9329.75) | 0.269 | |
Saliva | ||||
Top family | Flavobacteriaceae | 6784.5 (2604.5, 8936.5) | 8128 (7083, 10,112) | 0.289 |
Gemellaceae | 9110 (2739, 9895) | 3722 (2054, 5392) | 0.210 | |
Lactobacillaceae | 16,178 (5758, 25,449) | NA | ||
Micrococcaceae | 10,796 (6851, 22,256) | 5363 (5363, 5363) | 0.384 | |
Neisseriaceae | 27,814 (6188, 41,674) | 22,459 (9471.5, 30,426) | 0.695 | |
Porphyromonadaceae | 9893 (5834, 19,547.5) | 6259.5 (3340.25, 9906.75) | 0.093 | |
Prevotellaceae | 30,879 (9420.5, 39,816.5) | 20,346 (8663, 31,362) | 0.386 | |
Rivulariaceae | 52,390 (4881, 99,899) | NA | ||
Streptococcaceae | 37,934 (28,412, 47,562) | 52,361 (33,431, 62,602) | 0.156 | |
Veillonellaceae | 24,049.5 (9543.75, 36,522.5) | 26,681 (17,955, 34,776) | 0.536 | |
Top species | Calothrix parietina | 52,381.5 (4878, 99,885) | NA | |
Granulicatella adiacens | 11,447 (5475, 11,609) | NA | ||
Neisseria flavescens | 11,156 (6278, 16,034) | 10,976.5 (7555.75, 14,895.25) | 1.000 | |
Neisseria mucosa | 15,137 (9509.25, 29,842.25) | 10,501 (8133, 16,335) | 0.288 | |
Neisseria subflava | 12,388 (12,388, 12,388) | 4749 (4749, 4749) | 0.317 | |
Prevotella melaninogenica | 16,095 (12,500.5, 17,582) | 12,400 (6664, 17,685) | 0.273 | |
Rothia dentocariosa | 10,847 (10,847, 10,847) | NA | ||
Rothia mucilaginosa | 13,025.5 (5100.5, 20,090.75) | NA | ||
Unclassified at Species level | 47,894 (43,544, 57,892) | 48,100 (44,866, 54,567) | 0.846 | |
Veillonella atypica | 11,240 (8108, 15,829.75) | 11,364 (8764, 17,463) | 0.767 | |
Top phylum | Actinobacteria | 8467 (2359, 17,695) | 4542 (3117, 6773) | 0.097 |
Bacteroidetes | 43,222.5 (23,659.25, 52,389.25) | 30,558 (20,851, 43,199) | 0.279 | |
Chloroflexi | 1037 (1037, 1037) | NA | ||
Firmicutes | 76,819 (68,534, 96,665) | 100,930 (72,165, 107,327) | 0.263 | |
Fusobacteria | 3328 (2133, 5205) | 5466 (4048, 7725) | 0.018 | |
Proteobacteria | 15,284 (7899, 53,296) | 31,032 (11,128, 55,320) | 0.317 | |
Spirochaetes | 146 (111.25, 1249.5) | 190 (112.5, 304.5) | 0.847 | |
Thermi | 161.5 (64.75, 232) | NA | ||
Unclassified at Phylum level | 1131 (930, 1279) | 973 (807, 1028) | 0.135 | |
Verrucomicrobia | 221 (91, 328.5) | 134.5 (87.75, 242) | 0.495 | |