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Table 4 The Prediction performance using logistic regression with selected variables for each microbiota

From: 16S rRNA sequencing analysis of the oral and fecal microbiota in colorectal cancer positives versus colorectal cancer negatives in Iranian population

 

Variables

AUC (95% CI)

Cut-off

SE (95% CI)

SP (95% CI)

PPV (95% CI)

NPV (95% CI)

Accuracy (95% CI)

Saliva

Logistic-total variables

1.00 (1.00, 1.00)

1.00

1.00 (0.85, 1.00)

1.00 (0.78, 1.00)

1.00 (0.85, 1.00)

1.00 (0.79, 1.00)

0.39 (0.24, 0.57)

 

Logistic-selected variable

0.91 (0.82, 1.00)

0.60

0.87 (0.66, 0.97)

0.80 (0.52, 0.96)

0.87 (0.64, 0.97)

0.80 (0.54, 0.96)

0.84 (0.69, 0.94)

 

Support vector machine

0.90 (0.77, 1.00)

0.57

0.91 (0.72, 0.99)

0.87 (0.60, 0.98)

0.91 (0.70, 0.99)

0.87 (0.61, 0.98)

0.87 (0.72, 0.96)

 

Naïve Bayes

0.93 (0.84, 1.00)

0.10

0.91 (0.72, 0.99)

0.87 (0.60, 0.98)

0.91 (0.70, 0.99)

0.87 (0.61, 0.98)

0.89 (0.75, 0.97)

 

Neural network

0.64 (0.44, 0.83)

0.56

0.87 (0.66, 0.97)

0.53 (0.27, 0.79)

0.74 (0.48, 0.94)

0.73 (0.44, 0.90)

0.71 (0.54, 0.85)

Stool

Logistic-total variables

1.00 (1.00, 1.00)

1.00

1.00 (0.86, 1.00)

1.00 (0.77, NA)

1.00 (0.86, 1.00)

1.00 (0.78, 1.00)

0.36 (0.21, 0.53)

 

Logistic-selected variables

0.77 (0.59, 0.96)

0.58

0.76 (0.55, 0.91)

0.79 (0.49, 0.95)

0.86 (0.63, 0.95)

0.65 (0.41, 0.91)

0.77 (0.61, 0.89)

 

Support vector machine

0.97 (0.92, 1.00)

0.67

0.92 (0.74, 0.99)

0.93 (0.66, 1.00)

0.96 (0.78, 1.00)

0.87 (0.62, 1.00)

0.90 (0.76, 0.97)

 

Naïve Bayes

0.78 (0.61, 0.94)

0.76

0.60 (0.39, 0.79)

0.93 (0.66, 1.00)

0.94 (0.69, 0.97)

0.57 (0.35, 0.98)

0.69 (0.52, 0.83)

 

Neural network

0.45 (0.24, 0.66)

0.61

1.00 (0.86, 1.00)

0.21 (0.05, 0.51)

0.69 (0.29, 1.00)

1.00 (0.43, 1.00)

0.69 (0.52, 0.83)